Today is the Great American Smokeout, an opportunity for current smokers to kick the deadly habit not only for today but a lifetime.

This 37th annual observance, sponsored by the American Cancer Society, takes place on the third Thursday of November. The event aims to encourage smokers to use this date to make a plan to quit smoking or plan in advance to quit today.

Smoking, the greatest preventable cause of death, accounts for about one in every five U.S. deaths. Currently, about 45 million U.S. adults and 3 million youth smoke.

A New York Times article published this week offers a variety of resources and support tools to help smokers quit for good.

“Challenging, yes, but by no means impossible. On the Web you can download a Guide to Quitting Smoking, with detailed descriptions of all the tools and tips to help you become an ex-smoker once and for all,” reads the article.

According to Centers for Disease Control and Prevention data, smoking prevalence among people living with HIV/AIDS is estimated to be two to three times greater than in the general population.

Watch this recently produced video by the American Cancer Society that shines a harsh light on how Big Tobacco works to addict new users.